Make sure to not base align. Base aligning against inside zone (esp out of trips sets) causes your defense to lose outside contain because all your defenders are inside the tackles. Also shift your line to the side they are running towards.
This is applicable to any formation, but my favorite run defense is 3-4 c4. If you bring your safeties down a little bit, they will shoot down and blow up the run because they are in run fits.
Make sure to not base align. Base aligning against inside zone (esp out of trips sets) causes your defense to lose outside contain because all your defenders are inside the tackles. Also shift your line to the side they are running towards.
This is applicable to any formation, but my favorite run defense is 3-4 c4. If you bring your safeties down a little bit, they will shoot down and blow up the run because they are in run fits.